News » Archives » 2015

November 23, 2015

New finding offers hope for diabetic wound healing

Mayland Chang

University of Notre Dame researchers have discovered a compound that accelerates diabetic wound healing, which may open the door to new treatment strategies.

Read full article

November 20, 2015

New Notre Dame-Eli Lilly & Co. Faculty Fellowship Program in Drug Discovery Announced

Faculty researchers with an interest in the drug discovery process from across the University are invited to apply to spend a period of at least two to three months embedded within the chemistry program at Eli Lilly & Co. in Indianapolis, Indiana.

Eli Lilly & Co

Read full article

November 20, 2015

Research Like a Champion Today

The University of Notre Dame is full of brilliant students with innovative ideas that one day could change the world. Unfortunately, some ideas never get beyond the planning stage due to lack of funding.

That’s where a unique opportunity comes in. 

Research Like a Champion

Read full article

November 19, 2015

Hummon receives ACS Rising Star Award

amanda_hummon_square

Amanda Hummon, the Husking Foundation, Inc. Associate Professor of Chemistry and Biochemistry, has received a 2016 Rising Star Award from the American Chemical Society’s Women Chemists Committee. Hummon will accept the award at the national American Chemical Society (ACS) meeting in San Diego in March. 

Read full article

November 19, 2015

Director's Message, Fall 2015

Director’s Message, Fall 2015

Summer passed quickly, but before we delve into fall activities, I’d like to highlight some of our summer happenings at Harper Cancer Research Institute (HCRI). Earlier this summer, we welcomed the local community to our first HCRI Open House. Visitors were able to learn about advances in research from our scientists and trainees as well as to participate in a silent auction with proceeds benefiting Notre Dame Coaches vs.

Read full article

November 19, 2015

Researchers use nanotechnology to fight breast cancer

 

October is Breast Cancer Awareness Month, an annual campaign to increase awareness of the disease and the importance of early detection. Researchers at the University of Notre Dame are conducting innovative research aimed at improvements in early detection by molecular imaging.

Professors Ryan K. Roeder and Tracy Vargo-Gogola are combining their expertise in biomedical engineering and cancer biology, respectively, through the Harper Cancer Research Institute, a partnership between Notre Dame and the Indiana University School of Medicine-South Bend, to improve the accuracy of mammography for diagnosing breast cancer.

Read full article

November 19, 2015

Breast cancer researcher studies antioxidant connection

cancer cell

When it comes to fighting cancer, the enemy of our enemy could be our friend, according to a University of Notre Dame researcher.

As studies continue to suggest antioxidants could actually help cancer cells grow, the research of Zachary Schafer, the Coleman Foundation Associate Professor of Cancer Biology, can help explain why.

Read full article

November 19, 2015

Environment of tumors impacts metastasis, study finds

Siyuan Zhang

If a tumor is like a seed, the soil around it plays a significant role in its growth, a new study finds.

According to the study’s results, the microenvironment of a tumor cell has significant impact on cancer metastasis. This discovery by Siyuan Zhang at Notre Dame and a team at the University of Texas MD Anderson Cancer Center has focused attention on fighting cancer in the tumor cell’s microenvironment.

Read full article

November 19, 2015

Warren Family Research Center for Drug Discovery and Development partners with Retrophin and the Grace Wilsey Foundation

The Warren Family Research Center for Drug Discovery and Development at the University of Notre Dame has established a research collaboration with Retrophin, Inc. and the Grace Wilsey Foundation to focus on developing treatment for NGLY1 deficiency.    …

Read full article

November 19, 2015

The Changing Image of Cancer Research:  Cancer Engineering Wins at CABTRAC

As a collaboration between 50 academic institutions nationwide and the National Cancer Institute’s (NCI) Training Branch, the Cancer Biology Training Consortium (CABTRAC) brings together leaders in cancer research dedicated to training the next generation of cancer researchers, in part through NCI-sponsored training grants… Read more

Read full article

September 30, 2015

HCRI researchers win CTSI awards

Holly Weiss-Bilka, a postdoctoral associate in the Department of Biological Sciences, was awarded ‘best poster presentation’ in the postdoctoral division at the 2015 Indiana Clinical and Translational Sciences Institute (CTSI) annual meeting. As part of the award, Weiss-Bilka will receive $1,000 in research supply funds from the Indiana CTSI.

Read full article

September 15, 2015

Introducing Mary Galvin, dean of the College of Science

Mary Galvin, dean of the College of Science

Watch video Video

Mary Galvin, the William K. Warren Foundation Dean of the College of Science, sat down for a brief question-and-answer session about her experience, her passion for scientific research and her new role at the University of Notre Dame.

When asked what drew her to Notre Dame, Galvin is quick to answer: alignment with the University’s mission, and the chance to work with students again.

Read full article

September 15, 2015

Sharon Stack publishes book on HPV-associated oropharyngeal cancer

HPV

Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer worldwide. Although the overall incidence of HNSCC has decreased over the years due to public health efforts to promote smoking cessation, the incidence of oropharyngeal (tonsillar area) squamous cell carcinoma (OPSCC), which is associated with human papillomavirus (HPV), has increased over 200% from 1984-2004.

Read full article

September 15, 2015

CTSI Funding Opportunity for Early Stage Commercialization in Diagnostics and Therapeutics Development

SUBMISSION DEADLINETHURSDAY, OCTOBER 01, 2015 (5:00 PM).

A common critical gap in commercialization of technologies originating from the academic labs is the funding necessary to develop a robust commercialization relevant data package to reduce the risk of investment in early stage technologies. The Indiana CTSI

Read full article

September 11, 2015

New awards stimulate cutting-edge biomedical and environmental research at Notre Dame

AD&T

For a third consecutive year, the University of Notre Dame’s Advanced Diagnostics & Therapeutics (AD&T) initiative announced grant awards for a range of research projects that have the potential to solve significant problems in human and environmental health. The awards foster interdisciplinary research and promote new commercialization activity. Technologies developed through previous grants have been licensed by start-up companies, such as Contect and Enlightened Diagnostics, and spurred collaboration with external partners, including the Indiana University School of Medicine-South Bend, Saint Mary’s College, and Central Michigan University. This year’s projects show similar promise, and for the first time one was selected for joint funding by both AD&T and Notre Dame’s Harper Cancer Research Institute (HCRI).

Read full article

September 09, 2015

Lab Feature: Dr. Sharon Stack

With ovarian cancer ranking fifth in cancer deaths among women, there is an urgent need to increase research to improve early

sharon1_research_day_15

detection, develop new treatments and therapies, and methods for more effective imaging.  Currently, there is no reliable test to detect ovarian cancer in its earliest stages, so the majority of women with the disease are diagnosed after the tumor has already spread. Diagnosis in late stages of the disease dramatically reduces the effectiveness of current treatments and long-term survival. Dr. Sharon Stack, Director of the Harper Cancer Research Institute, and her lab are working to change these outcomes. Using primary and established human ovarian tumor cells and a variety of pre-clinical model systems, the Stack laboratory is investigating the role of changes in the expression and function of various enzymes and adhesion molecules in ovarian cancer metastasis.  More recent studies have begun to evaluate the role of the “host” tissues to ovarian cancer metastatic success.  For example, as the average age at which ovarian cancer is diagnosed is 63, research is addressing the hypothesis that ageing alters the ‘receptivity’ of tissues in the abdominal cavity to metastatic implantation by tumor cells. Additional studies evaluate the role that obesity plays in metastasis of ovarian cancer. Early results suggest that tumor cells adhere more aggressively to peritoneal tissues of mice fed on a high fat diet relative to control mice.…

Read full article

September 09, 2015

New Funding Opportunity to Support Pre-clinical Assays

Drug Development Services through the Molecular Therapeutics Program

SUBMISSION DEADLINE: October 15, 2015

The Molecular Therapeutics Program, a part of the Indiana Clinical and Translational Sciences Institute, has established a service agreement with Covance, Inc. to support early-stage drug discovery within CTSI

Read full article

September 03, 2015

Lieberman Awarded USAID Grant Seeded by CTSI Core Pilot Program

Paper test cards distinguish authentic and falsified oxycodone tablets

Professor Marya Lieberman has been awarded a grant from the US Agency for International Development (USAID) to monitor the quality of pharmaceuticals across western Kenya through the use of innovative diagnostic test cards developed in her laboratory. These inexpensive, point-of-need devices have been shown to detect falsified antibiotics, TB medications, and anti-malarial drugs. 

Read full article

September 03, 2015

Join Notre Dame Research at the Core Facility Fair

On Wednesday, September 16th, 2015, Notre Dame Research will host its annual Core Facility Fair from 10:00 a.m. to 2:00 p.m. in the Jordan Hall of Science Galleria.

Read full article

August 31, 2015

Helquist and Wiest awarded APMRF grant

WFRCDD Investigators and Professors of Chemistry & Biochemistry Paul Helquist and Olaf Wiest have been awarded a $100,000 grant from the Ara Parseghian Medical Research Foundation for “Design and Synthesis of Small Molecule Agents for Studies and Treatment of NPC

Read full article

August 31, 2015

Stahelin named recipient of Navari gift

Robert V. Stahelin, Ph. D., associate professor of biochemistry and molecular biology at Indiana University School of Medicine-South Bend (IUSM-SB), adjunct faculty in the Department of Chemistry & Biochemistry has been awarded the Navari Family Endowed Chair

Read full article

August 31, 2015

Patricia Clark elected to Executive Council of the Protein Society

Patricia Clark

Patricia Clark, the Rev. John Cardinal O'Hara C.S.C Professor of Biochemistry, has been elected to the executive council of the Protein Society. She will serve a three-year term (2015-18), during which she will work with the other councilors to organize and conduct the society’s business and help plan conferences and other activities for the organization’s membership.

Read full article

August 31, 2015

New publication: Human Papillomavirus (HPV)- Associated Oropharyngeal Cancer

Interested in head and neck squamous cell carcinoma? 
Check out a recently published book by Daniel Miller, University of Missouri, and edited by HCRI Director, Dr. Sharon Stack. 

Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer

Read full article

August 13, 2015

Notre Dame researcher part of team showing that 'humanized' mice can be used to study malaria

Mike Ferdig in his lab

University of Notre Dame researcher Mike Ferdig is part of team of researchers who have demonstrated that so-called “humanized” mice can be an effective model to study parasites that cause malaria and resistance to malarial drugs. Their study appears in the June 1 edition of the journal Nature Methods.

Read full article

August 13, 2015

Molly Duman Scheel receives Grand Challenges Explorations Grant

Molly Duman Scheel

Indiana University announced on Monday (Jun. 8) that Molly Duman Scheel, adjunct associate professor of biological sciences at the University of Notre Dame and associate professor of medical and molecular genetics at the Indiana University School of Medicine-South Bend (IUSM-SB), is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation. She will pursue an innovative global health and development research project, titled "Small Interfering RNA Larvicides for Control of Malaria Vector Mosquitoes." Read more…

Read full article

August 13, 2015

New Research Cluster at Notre Dame Accelerates Cancer Research

With cancer affecting millions of lives each year, Notre Dame scientists are working to develop personalized cancer vaccine therapies with the help of computational modeling. The recent acquisition of a General Purpose Graphics Processing Unit (GPGPU) compute cluster has significantly accelerated output for Notre Dame researchers. Led by Professor Brian Baker

Read full article

August 13, 2015

T-Cells: Tussling With Cancer

Michael Cosiano is one of several undergraduates working in Dr. Brian Baker's lab. The Baker lab focuses on the biophysics and structural biology of T- cell communication, and Michael is making important contributions to this work. Immunology is an incredibly important field linked to cancer research, and by furthering our understanding of the immune system he is helping better understand cancer. Read more…

Read full article

July 14, 2015

Notre Dame Researchers Work to Identify Mechanisms of Artemisinin Resistant Malaria

dhabinding

Notre Dame researchers, along with their collaborators, have identified a novel target of artemisinin that is crucial in understanding the mechanism of resistance in malarial parasites. These findings are reported in the April 30, 2015 issue of Nature. The team's results show that targeting PfPl3K will be vital to developing new therapies to combat artemisinin resistance.

Read full article

July 14, 2015

Graduate fellowships awarded for biomedical research at Notre Dame

Two students at the University of Notre Dame, each working on distinct technologies that could change the way cancer is understood and diagnosed, have been awarded the 2015/16 Berry Family Foundation Graduate Fellowships in Advanced Diagnostics & Therapeutics. Melinda Lake and Cody Narciso received the fellowships for their high-quality scholarship and the potential that their research could lead to significant improvements in Precision Medicine. Read more…

Read full article

July 14, 2015

Emil Hofman, professor emeritus of chemistry and former dean, dies at 94

Emil Hofman

Emil T. Hofman, professor emeritus of chemistry and former dean of the First Year of Studies at the University of Notre Dame, died Saturday morning (July 11). He was 94 years old.

Read full article