News » Archives » 2015

Faculty researchers with an interest in the drug discovery process from across the University are invited to apply to spend a period of at least two to three months embedded within the chemistry program at Eli Lilly & Co. in Indianapolis, Indiana.

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The University of Notre Dame is full of brilliant students with innovative ideas that one day could change the world. Unfortunately, some ideas never get beyond the planning stage due to lack of funding.

That’s where a unique opportunity comes in. 

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Amanda Hummon, the Husking Foundation, Inc. Associate Professor of Chemistry and Biochemistry, has received a 2016 Rising Star Award from the American Chemical Society’s Women Chemists Committee. Hummon will accept the award at the national American Chemical Society (ACS) meeting in San Diego in March. 

As a collaboration between 50 academic institutions nationwide and the National Cancer Institute’s (NCI) Training Branch, the Cancer Biology Training Consortium (CABTRAC) brings together leaders in cancer research dedicated to training the next generation of cancer researchers, in part through NCI-sponsored training grants... Read more

The Warren Family Research Center for Drug Discovery and Development at the University of Notre Dame has established a research collaboration with Retrophin, Inc. and the Grace Wilsey…

If a tumor is like a seed, the soil around it plays a significant role in its growth, a new study finds.

According to the study’s results, the microenvironment of a tumor cell has significant impact on cancer metastasis. This discovery by Siyuan Zhang at Notre Dame and a team at the University of Texas MD Anderson Cancer Center has focused attention on fighting cancer in the tumor cell’s microenvironment.

October is Breast Cancer Awareness Month, an annual campaign to increase awareness of the disease and the importance of early detection. Researchers at the University of Notre Dame are conducting innovative research aimed at improvements in early detection by molecular imaging.

Professors Ryan K. Roeder and Tracy Vargo-Gogola are combining their expertise in biomedical engineering and cancer biology, respectively, through the Harper Cancer Research Institute, a partnership between Notre Dame and the Indiana University School of Medicine-South Bend, to improve the accuracy of mammography for diagnosing breast cancer.

Director’s Message, Fall 2015

Summer passed quickly, but before we delve into fall activities, I’d like to highlight some of our summer happenings at Harper Cancer Research Institute (HCRI). Earlier this summer, we welcomed the local community to our…

Holly Weiss-Bilka, a postdoctoral associate in the Department of Biological Sciences, was awarded ‘best poster presentation’ in the postdoctoral division at the 2015 Indiana Clinical and Translational Sciences Institute (CTSI) annual meeting. As part of the award, Weiss-Bilka will receive $1,000 in research supply funds from the Indiana CTSI.

SUBMISSION DEADLINE – THURSDAY, OCTOBER…

Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer worldwide. Although the overall incidence of HNSCC has decreased over the years due to public health efforts to promote smoking cessation, the incidence of oropharyngeal (tonsillar area) squamous cell carcinoma (OPSCC), which is associated with human papillomavirus (HPV), has increased over 200% from 1984-2004.

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Mary Galvin, the William K. Warren Foundation Dean of the College of Science, sat down for a brief question-and-answer session about her experience, her passion for scientific research and her new role at the University of Notre Dame.

When asked what drew her to Notre Dame, Galvin is quick to answer: alignment with the University’s mission, and the chance to work with students again.

For a third consecutive year, the University of Notre Dame’s Advanced Diagnostics & Therapeutics (AD&T) initiative announced grant awards for a range of research projects that have the potential to solve significant problems in human and environmental health. The awards foster interdisciplinary research and promote new commercialization activity. Technologies developed through previous grants have been licensed by start-up companies, such as Contect and Enlightened Diagnostics, and spurred collaboration with external partners, including the Indiana University School of Medicine-South Bend, Saint Mary’s College, and Central Michigan University. This year’s projects show similar promise, and for the first time one was selected for joint funding by both AD&T and Notre Dame’s Harper Cancer Research Institute (HCRI).

Drug…

With ovarian cancer ranking fifth in cancer deaths among women, there is an urgent need to increase research to improve early

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Professor Marya Lieberman has been awarded a grant from the US Agency for International Development (USAID) to monitor the quality of pharmaceuticals across western Kenya through the use of innovative diagnostic test cards developed in her laboratory. These inexpensive, point-of-need devices have been shown to detect falsified antibiotics, TB medications, and anti-malarial drugs. 

On Wednesday, September 16th, 2015, Notre Dame Research will host its annual Core Facility Fair from 10:00 a.m. to 2:00 p.m. in the Jordan Hall of Science Galleria.

Robert V. Stahelin, Ph. D., associate professor of biochemistry and molecular biology at Indiana University School of Medicine-South…

WFRCDD Investigators and Professors of Chemistry & Biochemistry Paul Helquist and Olaf Wiest have been awarded a $100,000 grant from the Ara…

Interested in head and neck squamous cell carcinoma? 
Check out a recently published book by Daniel Miller, University of Missouri, and edited by HCRI Director, Dr. Sharon Stack. …

Patricia Clark, the Rev. John Cardinal O'Hara C.S.C Professor of Biochemistry, has been elected to the executive council of the Protein Society. She will serve a three-year term (2015-18), during which she will work with the other councilors to organize and conduct the society’s business and help plan conferences and other activities for the organization’s membership.

With cancer affecting millions of lives each year, Notre Dame scientists are working to develop personalized cancer vaccine therapies with the help of computational modeling. The recent acquisition of a General Purpose Graphics Processing Unit (GPGPU) compute cluster has…

Indiana University announced on Monday (Jun. 8) that Molly Duman Scheel, adjunct associate professor of biological sciences at the University of Notre Dame and associate professor of medical and molecular genetics at the Indiana University School of Medicine-South Bend (IUSM-SB), is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation. She will pursue an innovative global health and development research project, titled "Small Interfering RNA Larvicides for Control of Malaria Vector Mosquitoes." Read more...

University of Notre Dame researcher Mike Ferdig is part of team of researchers who have demonstrated that so-called “humanized” mice can be an effective model to study parasites that cause malaria and resistance to malarial drugs. Their study appears in the June 1 edition of the journal Nature Methods.

Michael Cosiano is one of several undergraduates working in Dr. Brian Baker's lab. The Baker lab focuses on the biophysics and structural biology of T- cell communication, and Michael is making important contributions to this work. Immunology is an incredibly important field linked to cancer research, and by furthering our understanding of the immune system he is helping better understand cancer. Read more...

Emil T. Hofman, professor emeritus of chemistry and former dean of the First Year of Studies at the University of Notre Dame, died Saturday morning (July 11). He was 94 years old.

Two students at the University of Notre Dame, each working on distinct technologies that could change the way cancer is understood and diagnosed, have been awarded the 2015/16 Berry Family Foundation Graduate Fellowships in Advanced Diagnostics & Therapeutics. Melinda Lake and Cody Narciso received the fellowships for their high-quality scholarship and the potential that their research could lead to significant improvements in Precision Medicine. Read more...

Notre Dame researchers, along with their collaborators, have identified a novel target of artemisinin that is crucial in understanding the mechanism of resistance in malarial parasites. These findings are reported in the April 30, 2015 issue of Nature. The team's results show that targeting PfPl3K will be vital to developing new therapies to combat artemisinin resistance.